Abstract Library

#3858 OTP, CD44, and Ki-67 – A prognostic marker panel for relapse free survival in patients with surgically resected pulmonary carcinoid

Introduction: Relapse occurs in 10% of patients with resected pulmonary carcinoid (PC). While typical carcinoids (TC) show low relapse rates, safe exclusion from long-term follow-up (FU) is impossible partly due to high interobserver variation in the WHO classification.

Conference:

Presenting Author: Moonen L

Authors: Moonen L, Derks J, den Bakker M, Hillen L, von der Thüsen J,

Keywords: Pulmonary Carcinoid, OTP, CD44, Ki-67, biomarker, prognosis,

#3462 Development and verification of a new monoclonal OTP specific antibody for pulmonary carcinoid diagnostics

Introduction: Histology-based grading of pulmonary carcinoids (PC) is problematic and subject to high interobserver variation. Orthopedia homeobox (OTP) has shown to be an excellent prognostic marker for PCs, also indicated by the WHO. However, absence of a reliable routinely applicable monoclonal OTP antibody (mAb) hampers implementation in routine diagnostics.

Conference:

Presenting Author: Speel E

Authors: Moonen L, Derks J, Lap L, Marijnissen B, van den Bosch T,

Keywords: Orthopedia Homeobox, pulmonary carcinoid, monoclonal antibody, clinical diagnostics,

#653 Interobserver Variability of Pulmonary Carcinoids

Introduction: Lung carcinoids are neuroendocrine tumors histopathologically classified into typical (TC; no necrosis,

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Swarts D, Van Suylen R, Den Bakker M, Van Oosterhout M, Thunnissen E,

Keywords: lung carcinoids, classification, histopathology, interobserver variation, orthopedia homeobox, MIB-1,