Abstract Library

#4177 Performance of a prognostic OTP, CD44, Ki-67 biomarker panel on paired biopsies and resections of lung carcinoids

Introduction: Previously OTP, CD44 and ki-67 have been identified as prognostic biomarkers for lung carcinoid (LC).

Conference:

Presenting Author: van Weert T

Authors: van Weert T, Moonen L, Hillen L, von der Thüsen J, Lap L,

Keywords: OTP, CD44, Ki-67, lung carcinoid, relapse prediction,

#3858 OTP, CD44, and Ki-67 – A prognostic marker panel for relapse free survival in patients with surgically resected pulmonary carcinoid

Introduction: Relapse occurs in 10% of patients with resected pulmonary carcinoid (PC). While typical carcinoids (TC) show low relapse rates, safe exclusion from long-term follow-up (FU) is impossible partly due to high interobserver variation in the WHO classification.

Conference:

Presenting Author: Moonen L

Authors: Moonen L, Derks J, den Bakker M, Hillen L, von der Thüsen J,

Keywords: Pulmonary Carcinoid, OTP, CD44, Ki-67, biomarker, prognosis,

#3409 Ascl1 and OTP identify four prognostic groups among atypical carcinoids

Introduction: Atypical Carcinoids (AC) according World Health Organization guidelines are well differentiated Lung Neuroendocrine tumor with 2-10 mitoses/2 mm2 and/or with necrosis. Besides morphological differentiation no further tools in predicting AC clinical outcome are proposed.

Conference:

Presenting Author:

Authors: Centonze G, Maisonneuve P, Grillo F, Mangogna A, Prinzi N,

Keywords: Atypical Carcinoid, lung, ascl1, otp,

#2050 Finding the Ways to Determine the Prognosis of Pulmonary Carcinoids with Certain Genes/Markers in Pakistan

Introduction: Pulmonary neuroendocrine tumors are classified into four subtypes from well differentiated to poorly differentiated high grade large cell neuroendocrine carcinomas. Because of the difficult histological classification and a cancer free period following surgery, it is often difficult to predict certain prognostic factors.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Fatima A

Authors: Fatima A, Zaidi S,

Keywords: prognostic markers, CD44, OTP, genes regulation, cancer prognosis,

#1115 Cancer Stem Cells in Small Intestine Neuroendocrine Cell Line P-STS: Isolation and Molecular Characterisation

Introduction: Cancer stem cells (CSCs) represent a small subpopulation of tumour cells responsible for invasive tumour growth. Even though the presence of CSCs in neuroendocrine tumours is documented, their role in neuroendocrine tumourigenesis and metastasis is not defined as yet.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Kleinegger F, Meier-Allard N, Fuchs R, Hölzl M, Krump C,

Keywords: Cancer stem cells, tumor growth, tumorigenesis & metastasis,