Abstract Library

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#4648 Analysis of presentation and outcomes of mixed adenoneuroendocrine carcinoma (MANEC) – A single centre experience

Introduction: Mixed adenoneuroendocrine carcinoma (MANEC) is a rare neoplasm characterised by the coexistence of both adenocarcinoma and neuroendocrine carcinoma components. Due to its rarity, limited data exist regarding its clinical presentation, treatment strategies, and outcomes. This study provides an analysis of MANEC cases from a single centre, providing insights into its clinical features, diagnostic challenges, treatment strategies, and prognosis.

Conference:

Presenting Author: Khosla D

Authors: Khosla D, Kapoor R, Mehta A, Gupta R, Singh H,

Keywords: MANEC, mixed adenoneuroendocrine carcinoma, treatment,

#2855 Whole Exome Sequencing Reveals the Monoclonal Origin of Gastric Mixed Adenoneuroendocrine Carcinomas

Introduction: Gastric mixed adenoneuroendocrine carcinomas (g-MANECs) are rare neoplasms consisting of adenocarcinoma and neuroendocrine neoplastic components. G-MANECs show more malignant characteristics than gastric adenocarcinomas, while molecular mechanisms underlying the co-existence of the two components remains unknown.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Yan S, Chen X, Zhang R, Song L, Yin F,

Keywords: whole exome sequencing, mixed adenoneuroendocrine carcinoma, Stomach, Evolution,

#2257 Poorly Differentiated Neuroendocrine Carcinomas of the Colon: A Clinicopathological Study

Introduction: Neuroendocrine carcinomas (NEC) of the colon and rectum are aggressive and rare tumours. The Digestive Tract WHO classification 2010 defines the entity of large cell NEC (LCNEC) in contrast to small cell NEC (SCNEC).

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Boeck I

Authors: Boeck I, Weihe E, Krieg A, Gabbert H, Raffel A,

Keywords: GEP-NEC, LCNEC, Colonic NEC,

#2250 Treatment Outcomes of Patients with Mixed Neuroendocrine Non-Neuroendocrine Neoplasms (MiNEN)

Introduction: Mixed neuroendocrine non-neuroendocrine neoplasms (MiNEN) have been newly defined in the WHO 2017 classification. They are rare tumors, commonly treated in analogy to their non-neuroendocrine (nNE) or neuroendocrine (NE) component without systematic data regarding the optimal therapeutic strategy.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Apostolidis L, Bergmann F, Haag G, Jäger D, Winkler E,

Keywords: MiNEN, mixed neuroendocrine non-neuroendocrine neoplasm, MANEC, mixed adenoneuroendocrine carcinoma,

#2170 Clinical Characteristics and Prognostic Analysis of 14 Patients with Gastric Mixed Adenoneuroendocrine Carcinoma

Introduction: To investigate the clinical characteristics and prognostic factors of patients with gastric mixed adenoneuroendocrine carcinoma(MANEC)．

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Bei X,

Keywords: gastric MAENC, neural invasion, lymph node involvement, prognosis,