Abstract Library

#3241 Clinical features and management of paragangliomas in a tertiary university hospital

Introduction: Paragangliomas (PG) are rare neuroendocrine tumors that arise from the extra-adrenal paraganglia. The most frequent location is head and neck PG (HNPG), usually non-functioning tumors. PG present a high rate of genetic susceptibility mainly associated with SDHx mutation. Clinical presentation depends upon catecholamine secretion and tumor location. Surgery remains the standard treatment, although radiotherapy and systemic therapies can be considered for unresectable or metastatic disease.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Damaso S, Lopes Brás R, Paiva R, Macedo D, Fernandes I,

Keywords: paraganglioma, treatment, sdhb gene,

#2908 Re-Cellularised Human Pancreas 3D Scaffolds as a Novel Model for Biomarker Discovery in Pancreatic Neuroendocrine Tumours (pNETs)

Introduction: The lack of preclinical models of pNETs has challenged identification of tissue specific biomarkers of disease. Culturing cancer cells in their native tissue enables the close study of cell-ECM interaction and tissue remodelling. The biological products of such interactions can form a basis for discovery of novel biomarkers of the disease, and were previously linked with a range of inflammatory and malignant conditions.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Ney A

Authors: Ney A, Al-Akkad W, Frenguelli L, Acedo P, Mazza G,

Keywords: 3d models, pancreatic neuroendocrine tumors, Biomarkers,

#1816 Multivisceral Transplantation and Vascularised Sentinel Forearm Flap for a Metastatic Small Bowel Neuroendocrine Tumour: Update on Follow-Up

Introduction: We previously reported the first documented case of a novel approach in a patient with extensive mesenteric metastases from a small bowel neuroendocrine tumour (SBNET): this combined multivisceral transplantation (MVT) and a vascularised sentinel forearm flap (VSFF) from the same donor.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Frilling A

Authors: Frilling A, Giele H, Vrakas G, Reddy S, Macedo R,

Keywords: small bowel neuroendocrine tumour, multivisceral transplantation, forearm flap, follow-up,

#1558 Multivisceral Transplantation and Vascularised Sentinel Forearm Flap for a Metastatic Gut-Derived Neuroendocrine Tumour: Follow-up

Introduction: We previously reported the first documented case of a novel approach in a patient with extensive mesenteric metastases from a small bowel (SB) NET: this combined multivisceral transplantation (MVT) and a vascularised sentinel forearm flap (VSFF) from the same donor.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Malczewska A

Authors: Clift A, Giele H, Vrakas G, Reddy S, Macedo R,

Keywords: neuroendocrine, transplantation, multivisceral, forearm flap,

#1113 A Novel Approach for a Metastatic Gut-Derived Neuroendocrine Tumour: Simultaenous Intestinal and Vascularised Sentinel Forearm Flap Transplantation

Introduction: Non-resectable tumours involving the mesenteric root are an indication for intestinal and multivisceral transplantation (MVT). Vascularised sentinel forearm flaps (VSFF) offer possibilities for monitoring graft rejection and tailoring immunosuppression (IS) regimens.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Frilling A

Authors: Clift A, Giele H, Vrakas G, Reddy S, Macedo R,

Keywords: neuroendocrine, tumor, transplantation,