Abstract Library

#4229 Bone health in neuroendocrine neoplasms

Introduction: Neuroendocrine neoplasms (NENs) are a heterogeneous group of rare neoplasms, classified according to localization of the primary tumor, differentiation and grading. The effect of localized or advanced NENs and systemic therapies on bone and muscle health is still controversial.

Conference:

Presenting Author:

Authors: Casabella A, Veresani A, Boschetti M, Sulli A, Hasballa I,

Keywords: Bone health, neuroendocrine neoplasm, TBS, RSMI, T-Score,

#3765 Heterogeneity and potential therapeutic targets of rectal neuroendocrine tumors by single cell RNA-sequencing combined with spatial omics

Introduction: The incidence of rectal neuroendocrine tumors (rNETs) has increased rapidly in the past 30 years. However, the molecular mechanism of its occurrence and development is still unclear, and the basic research is relatively backward.

Conference:

Presenting Author:

Authors: Bai J, Tang Q,

Keywords: neuroendocrine tumor, single cell RNA sequencing, spatial transcriptome, heterogeneity, tumor microenvironment, phospholipase d3, metastasis,

#3604 Preoperative acute pancreatitis and hyperenzymemia are associated with poor prognosis in patients with non-functional pancreatic neuroendocrine tumors

Introduction: Acute pancreatitis (AP) and hyperenzymemia have been studied regarding their incidences and potential prognostic value in pancreatic cancer and intraductal papillary mucinous neoplasm. However, currently, the knowledge of the relationship between AP/ hyperenzymemia and pancreatic neuroendocrine tumors (PNETs) is from few cases reports or series.

Conference:

Presenting Author: Tan Q

Authors: Tan Q, Song H, Cao D, Wang X, Liu X,

Keywords: Acute pancreatitis, amylase, lipase, pancreatic neuroendocrine tumor, prognosis,

#3158 Incidence of brain metastases (BMs) and outcomes in patients (pts) with extrapulmonary neuroendocrine neoplasms (EP-NENs)

Introduction: The incidence, management and outcomes of pts with EP-NENs and BMs are unclear.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Kapacee Z, Dawod M, Allison J, Frizziero M, Chakrabarty B,

Keywords: brain metastases, extrapulmonary NENs, radiotherapy, whole brain radiotherapy, survival, grade 3 NEC,

#2927 Systemic Chemotherapy for Inoperable Goblet Cell Adenocarcinomas (GCAs) and the Role of Anti-EGFR Antibodies

Introduction: Appendiceal GCAs (previously Goblet Cell Carcinoids) have variable behaviour. Systemic chemotherapy (Chemo) is often extrapolated from colon cancer. KRAS mutations (KRAS-mut) are rare and more often present in Tang-C/high grade. The role of anti-EGFR antibodies (MoAb) is unknown.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Barriuso J, Martin A, Chakrabarty B, Burghel G, Lamarca A,

Keywords: goblet cell adenocarcinomas, chemotherapy, anti-egfr,