Abstract Library

#4584 Hepatic cytoreduction in advanced lung neuroendocrine neoplasms: A single institutional case series

Introduction: Role of hepatic cytoreductive surgery in well-differentiated gastroenteropancreatic neuroendocrine neoplasms (NENs) with liver metastases is well-described, however, its role in advanced lung NENs with liver metastases is unknown.

Conference:

Presenting Author: Grewal U

Authors: Grewal U, Patel R, Furqan M, Dillon J, Chandasekharan C,

Keywords: Lung neuroendocrine neoplasm, Hepatic cytoreductive surgery,

#4536 Follow-up is not justified in patients with typical lung carcinoids treated with curative intent

Introduction: Typical carcinoids (TC) are well-differentiated neuroendocrine neoplasms of the lung with generally favourable prognosis. Recurrence is rare in TC patients treated with curative intent, yet current ENETS guidelines recommend extensive follow-up, including regular and long-term imaging.

Conference:

Presenting Author: Lau T

Authors: Lau T, Soldath P, Rewitz K, Jepsen P, Knigge U,

Keywords: typical carcinoid, lung nen, follow-up programme,

#4203 The diagnostic role of DWI-MRI for liver metastases of neuroendocrine neoplasms (NENs) in comparison with the functional imaging

Introduction: A combination of morphological and functional imaging plays a crucial role for diagnosis, staging and therapeutic decision for neuroendocrine neoplasms (NENs). Diffusion-weighted imaging (DWI) magnetic resonance imaging (MRI) is emerging as a key imaging technique in the NEN field.

Conference:

Presenting Author: Sesti F

Authors: Feola T, Sesti F, Centello R, Filice A, Pirisino R,

Keywords: MRI, DWI, PET, Liver metastases,

#3576 Patterns of family history of cancer and associated risk of developing neuroendocrine tumors: A cross-sectional study

Introduction: Except for known hereditary syndromes (mostly, multiple endocrine neoplasia type I and von Hippel Lindau), familial clustering of cancers in patients (pts) with neuroendocrine neoplasms (NEN) is scarcely reported.

Conference:

Presenting Author: Viapiana P

Authors: Viapiana P, Dias C, Cruz Formiga M, Simões Riechelmann R,

Keywords: neuroendocrine tumor, family history,

#3568 Exploring the interplay between chromatin-remodeling genes and the regulation of alternative splicing and RNA biology in lung neuroendocrine neoplasms

Introduction: Lung neuroendocrine neoplasms (LungNENs) comprise a heterogeneous group of rare tumors, but with a rising incidence in the last decades. The mutational landscape of LungNENs has been recently described; in contrast, other key regulatory mechanisms, particularly posttranscriptional processes linked to RNA regulation, remain largely unexplored.

Conference:

Presenting Author: Agraz-Doblas A

Authors: Agraz-Doblas A, Blázquez-Encinas R, Victor G, Alcala N, Sexton-Oates A,

Keywords: Lung NEN, Bioinformatics, Chromatin-remodeling, RNA, biomarker, mutations,