Abstract Library

#4033 Routine early 68Ga-DOTATATE PET/CT has low diagnostic yield after resection of pancreatic neuroendocrine neoplasms

Introduction: Following resection of primary pancreatic neuroendocrine neoplasm (P-NEN), the reported median disease free survival is ≥4y. 68Ga-DOTATATE PET/CT (DOTA-PET) is widely used for restaging following surgical resection of P-NEN due to a higher sensitivity compared to cross-sectional imaging. We hypothesized that early DOTA-PET has a low yield in detecting recurrent/residual or distant disease in patients following curative-intent surgical resection of non-metastatic localised P-NEN.

Conference:

Presenting Author:

Authors: Singh A, Chan D, Samra J, Pavlakis N, Engel A,

Keywords: Pancreatic NEN, post-resection, restaging, early 68Ga-DOTATATE PET/CT, diagnostic yield,

#3586 Grading diagnostic accuracy of EUS Tissue Acquisition in pancreatic neuroendocrine tumors: A systematic review and meta-analysis

Introduction: Pancreatic neuroendocrine neoplasms (PanNENs), are a form of neoplasms arising from cells of the endocrine and nervous systems. Grading (G) is one of the most important decisional factor for therapy as is associated with prognosis, overall survival and disease free survival decrease. Endoscopic ultrasound fine needle-aspiration/biopsy (EUS-FNA/B) is the gold standard for diagnosing PanNENs and Ki67 evaluation, but data regarding accuracy and concordance with post-surgical histological examination are scanty and heterogeneous.

Conference:

Presenting Author:

Authors: Tacelli M, Bina N, Crinò S, Facciorusso A, Barresi L,

Keywords: endoscopic ultrasound, net, ki67, who, misclassification,

#2957 New Evidence of Emerging Nodal Metastasis in Staging System after Surgical pNET Resection as Predictive Factor for Recurrence. Result from Monocentric Retrospective Series

Introduction: New evidence is emerging of the role of pNETs lymphatic metastasis in terms of Oncological Outcomes. A specific staging classification is not actually available.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Mastrangelo l

Authors: Mastrangelo L, Romboli A, Masetti M, Zanello M, Cipressi C,

Keywords: lymph node status, neuroendocrine tumor, pancreas, prognosis, surgery,

#2725 Upfront Surgery in Patients with High-Grade GEP NEN and MINEN: A Nordic Multicenter Study of 201 Patients

Introduction: Surgery is the principal treatment for loco-regional gastroenteropancreatic (GEP) neuroendocrine tumors (NET). However, whether surgery is beneficial in high-grade neuroendocrine neoplasms (NEN) and mixed neuroendocrine-non neuroendocrine neoplasms (MiNEN) is not known.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Pommergaard H

Authors: Pommergaard H, Nielsen K, Sorbye H, Federspiel B, Tabaksblat E,

Keywords: surgery, neuroendocrine carcinoma, MiNEN, neuroendocrine neoplasms, survival, gastroenteropancreatic,

#2200 Tumor Size Correlates with Grading in Nonfunctioning Pancreatic Neuroendocrine Tumors and Is Not Age-Dependent

Introduction: Tumor growth and Ki67 value increase are associated with aggressiveness in nonfunctioning pancreatic neuroendocrine tumours (NF-PanNET), but their natural history is largely unknown. It is unknown if the evolution of NF-PanNET is time-dependant.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Muffatti F

Authors: Muffatti F, Partelli S, Rancoita P, Andreasi V, Giannone F,

Keywords: NF-PanNET, tumor size, age, Ki-67,