Abstract Library

#2148 Tumor Microenvironment in Merkel Cell Carcinoma: Association with Merkel Cell Polyomavirus and Clinico-Pathological Features in a Retrospective Cohort Study

Introduction: MCC is a rare and aggressive skin cancer with a neuroendocrine phenotype.Association between MCC and Polyomavirus is known.PD-1 and PD-L1 have recently become key players in the therapeutic landscape.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Birocco N

Authors: Mecca C, Maletta F, Caliendo V, Birocco N, Metovic J,

Keywords: merkel cell carcinoma, microenvironment, polyomavirus,

#1402 Merkel Cell Carcinoma of Lymph Node Without Skin Primary Can - and Should - Be Distinguished from Others Metastatic Neuroendocrine Carcinoma

Introduction: Merkel cell carcinoma of lymph node without primary tumour (MCCNWP) is a rare tumour which can be misinterpreted as lymph node metastasis (LNM) from a high-grade neuroendocrine carcinoma (NEC) on histological examination. However, this distinction is crucial for therapeutic management.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: KERVARREC T

Authors: Kervarrec T, Samimi M, Beby-Defaux A, Touze A, Guyetant S,

Keywords: Merkel cell carcinoma, lymph node, MCPyV,

#1129 Expression and Clinical Significance of Merkel Cell Polyomavirus Large T Antigen in Merkel Cell Carcinoma

Introduction: Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer that is often associated with Merkel cell polyomavirus (MCPyV) infection. MCPyV expression and its relationship with clinical features and prognosis in MCC remain unclear.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Delektorskaya V, Orlova K, Smirnova E, Demidov L,

Keywords: merkel cell carcinoma, merkel cell polyomavirus, immunohistochemistry, prognosis,

#69 Frequent biological association of Merkel cell polyomavirus with Merkel cell carcinomas

Introduction: Merkel cell polyomavirus (MCPyV) DNA has been detected by PCR in 75–100% of Merkel cell carcinomas (MCC), an aggressive neuroendocrine skin cancer. MCPyV is a 5.4 kb DNA virus that expresses tumor (T) antigen in tumor tissues.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Speel E

Authors: Speel E, Schmidt A, Baumann M, Haesevoets A, Diebold J,

Keywords: Merkel cell polyoma virus, Merkel cell carcinoma, neuroendocrine skin cancer, FISH, large T antigen,