Abstract Library

#2855 Whole Exome Sequencing Reveals the Monoclonal Origin of Gastric Mixed Adenoneuroendocrine Carcinomas

Introduction: Gastric mixed adenoneuroendocrine carcinomas (g-MANECs) are rare neoplasms consisting of adenocarcinoma and neuroendocrine neoplastic components. G-MANECs show more malignant characteristics than gastric adenocarcinomas, while molecular mechanisms underlying the co-existence of the two components remains unknown.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Yan S, Chen X, Zhang R, Song L, Yin F,

Keywords: whole exome sequencing, mixed adenoneuroendocrine carcinoma, Stomach, Evolution,

#1849 Mixed Adeno-Neuroendocrine Carcinoma (MANEC) of the Gastrointestinal (GI) Tract: Experience of a European Neuroendocrine Tumour Society (ENETS) Centre of Excellence

Introduction: Knowledge of MANECs is limited

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Frizziero M, Wang X, Chakrabarty B, Mansoor W, Fulford P,

Keywords: manec, gastroinstestinal tract, overall survival,

#1204 Clinico-Pathologic and Survival Analysis of 211 GastroEnteroPancreatic G3 Neuroendocrine Carcinomas (GEP-NECs)

Introduction: GEP-NECs show Ki67>20% and/or >20 mitoses x10 HPF. Mixed AdenoNeuroendocrine Carcinomas (MANECs) are mixed exocrine-neuroendocrine neoplasms. NECs are associated with poor prognosis but recent findings have suggested that there is a fraction of patients showing a better than expected survival rate.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Milione M

Authors: Milione M, Spada F, Maisonneuve P, Pusceddu S, Spaggiari P,

Keywords: NEC, Ki67, MANEC, PROGNOSIS,

#1159 Mixed Adenoneuroendocrine Carcinomas (MANECs) of the Gastrointestinal Tract. ARGENTUM Group

Introduction: Mixed adenoneuroendocrine carcinomas of the gastrointestinal tract are rare neoplasms. In the 2000 WHO classification of endocrine tumors, such neoplasms were defined as mixed exocrine-endocrine tumors when each component represents at least 30% of the lesion. In the most recent WHO classification, such neoplasms are called “mixed adenoneuroendocrine carcinomas” (MANECs). They are a challenge for the diagnostic and treatment.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Cabanne A, Bestani C, Pesce V, O'Connor J, Kujaruk M,

Keywords: MANEC, NETs,

#1087 Gastro-Entero-Pancreatic Mixed Adenoneuroendocrine Tumors. Report of Four Cases.

Introduction: Mixed adenoneuroendocrine carcinomas (MANECs) is an uncommon entity with ill-defined clinicopathologic characteristics.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: we do not want to present it orally

Authors: Koletsa T, Iliadis A, Tzioufa V, Karayannopoulou G,

Keywords: Mixed adenoneuroendocrine tumors, immunohistochemistry, MMR proteins, MSI,