Abstract Library

#2121 Phase II Study of Temozolomide Monotherapy in Patients of Neuroendocrine Carcinoma with Resistant to Platinum-Based Chemotherapy

Introduction: Neuroendocrine carcinomas (NEC) (high grade Ki67 > 20%) were poor prognostic and lethal disease. Platinum-based chemotherapy is usually chosen as a first line treatment for advanced NEC, however, this efficacy is temporary and there is no standard second-line treatment yet. Temozolomide is a good candidate, however it was not approved for NEC by Japanese authorities.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Ichikawa Y, Kobayashi N, Tokuhisa M, Goto A, Hiroshima Y,

Keywords: Neuroendocrine Carcinoma, Temozolomide,

#930 Distinct Expression of Splicing Variants of the Human MEN1 (Multiple Endocrine Neoplasia Type 1) Gene in Various Pituitary Adenomas

Introduction: MEN1 is an autosomal-dominant tumor syndrome characterized by the occurrence of tumors in multiple endocrine tissues, including parathyroid, enteropancreatic neuroendocrine and anterior pituitary. The MEN1 gene consists of 10 exons transcribed into a 610 a.a. protein. It was reported that heterogeneity of human MEN1 gene transcripts related to variation in their 5’ UTR. Six distinct exsons1 (e1A-e1F) were isolated using RNA from thymus, pancreas and kidney.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Ozawa A

Authors: Ozawa A, Watanabe T, Tosaka M, Yoshimoto Y, Horiguchi K,

Keywords: MEN1, pituitary,

#926 Transarterial (Chemo)embolization for Patients with Liver Metastasis of Neuroendocrine Tumors

Introduction: Neuroendocrine Tumors (NETs) are slowly growing tumors with an indolent course. NETs often present with liver metastasis, and most of these tumors are inoperable at the time of presentation. Transarterial (chemo)embolization [TA(C)E] is widely available to manage liver metastasis of NET.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Okuyama H, Takahashi H, Ohno I, Shimizu S, Mitsunaga S,

Keywords: neuroendocrine tumor, TACE, TAE,

#830 The Predictive Value of Gastrin Levels for the Diagnosis of Gastric Enterochromaffin-like Cells Hyperplasia, in Patients with Hashimoto’s Thyroiditis

Introduction: Gastrin and chromogranin A (CgA) levels have been tested for the diagnosis of enterochromaffin-like cell hyperplasia (ECLH), in patients with type 1 diabetes and autoimmune atrophic gastritis but there are no data for patients with Hashimoto's thyroiditis (HT).

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Nikolaou A, Thomas D, Alexandraki K, Sougioultzis S, Tsolakis A,

Keywords: enterochromaffin-like cell hyperplasia, gastrin, thyroiditis,

#633 Clinical and Prognostic Features of Neuroendocrine Tumor of Unknown Primary Site

Introduction: Neuroendocrine tumors of unknown primary site (NET UPS) are rare and heterogenous tumors with poor prognosis. There is little information available on the treatment and prognosis.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Shim H

Authors: Shim H, Kim D, Hwang J, Lee K, Cho S,

Keywords: neuroendocrine tumor, unknown primary site,