Abstract Library

#4496 ATRX, DAXX, and menin immunohistochemistry identify prognostic relevant non-functioning neuroendocrine tumours subgroups

Introduction: Non-functioning pancreatic neuroendocrine tumours (NF-pNETs) are rare tumours with a variable prognosis. Recent studies have identified prognostic subgroups based on ATRX, DAXX and MEN1 mutations along with chromosomal aneuploidies.

Conference:

Presenting Author: Verschuur A

Authors: Verschuur A, Jairam J, Eldem B, Singhi A, Hackeng W,

Keywords: pancreatic neuroendocrine tumour, ATRX, DAXX, MEN1, menin, biomarker,

#4462 Clustering of gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) using machine learning (ML) and comparison with tumour, node, metastasis (TNM) staging: A population-based study using surveillance, epidemiology, and end results (SEER)

Introduction: TNM 8 is the staging system for GEP-NEN, guiding prognosis and treatment. However, it does not include important prognostic factors such as age, sex, race, and morphology.

Conference:

Presenting Author: Mortagy M

Authors: Mortagy M, El Asmar M, White B, Chandrakumaran K, Ramage J,

Keywords: Clustering, Machine learning, GEP-NEN, TNM Staging, Survival Analysis, SEER,

#4348 Real-world clinicopathological features and outcome of elderly patients with thymic neuroendocrine neoplasms: A retrospective single-institution analysis

Introduction: Thymic neuroendocrine neoplasms (TNENs）are rare and heterogeneous diseases. With the aging of society, there has been an increase in the proportion of elderly patients with TNENs，however, research on these patients is limited.

Conference:

Presenting Author:

Authors: Jia X, Sun Z, Xu J, Huang D, Chen F,

Keywords: thymic neuroendocrine tumour, aged 65 years or above, clinicopathological characteristics, survival analysis, real-world,

#4255 Prognostic significance of nodal micrometastases in patients with non-functioning pancreatic neuroendocrine tumors (NF-PanNETs) – A survival analysis from a prospective observational study

Introduction: Nodal metastases (N+) are one of the most powerful predictors of disease recurrence after surgery for non-functioning pancreatic neuroendocrine tumors (NF-PanNETs). However, the prognostic role of nodal metastases

Conference:

Presenting Author: Andreasi V

Authors: Andreasi V, Partelli S, Schiavo Lena M, Muffatti F, Battistella A,

Keywords: nodal metastases, micrometastases, surgery, prognosis, recurrence, pancreatic neuroendocrine,

#4114 Delays in the dosing administration of PRRT in advanced neuroendocrine tumors – Is there an adverse impact?

Introduction: Peptide receptor radionuclide therapy (PRRT) has emerged as a major therapeutic component in the overall management of advanced neuroendocrine tumors (NETs). In Greece, the treatment has been performed for several years, however because of reimbursement issues, especially during the financial crisis in Greece, there is usually a delay between the administered doses beyond the recommended 6-8 weeks interval.

Conference:

Presenting Author:

Authors: Georgakopoulos A, Tsoli M, Koumarianou A, Papadopoulou N, Panagaki M,

Keywords: PRRT, Progression-free survival, overall survival,