Abstract Library

#4175 Immunohistochemical profiling of lung carcinoid subtypes and marker comparison of matched primary and metastatic tumors

Introduction: Multi-omic studies have identified three lung carcinoid (LC) subtypes (A1, A2, B) with unique gene expression for OTP, ASCL1 & HNF1a.

Conference:

Presenting Author: Leunissen D

Authors: Leunissen D, Moonen L, von der Thüsen J, den Bakker M, Hillen L,

Keywords: lung carcinoid, TTF1, S100, metastatic disease,

#4174 Uncovering the genomic profiling of metastatic pheochromocytomas and paragangliomas: Leveraging plasma circulating tumor DNA for comprehensive genetic characterisation and monitoring

Introduction: Liquid biopsy, notably plasma circulating tumor DNA (ctDNA), is a non-invasive approach to elucidate the tumoral genomic profile from a blood sample. Pheochromocytomas and paragangliomas (PPGL) are often operated, characterized by quiet genomes and usually indolent tumor growth. However, challenges arise with metastatic tumors due to accessibility, catecholamine-related crises and surgery issues. Thus, molecular mechanisms transitioning from indolent to metastatic tumors are largely unexplored.

Conference:

Presenting Author:

Authors: Arenillas Lallana C, Moreno-Cárdenas A, Casteràs A, García-Álvarez A, Hernando J,

Keywords: liquid biopsy, ctDNA, metastasis, pheochromocytoma, paraganglioma, genomic targets,

#1129 Expression and Clinical Significance of Merkel Cell Polyomavirus Large T Antigen in Merkel Cell Carcinoma

Introduction: Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer that is often associated with Merkel cell polyomavirus (MCPyV) infection. MCPyV expression and its relationship with clinical features and prognosis in MCC remain unclear.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Delektorskaya V, Orlova K, Smirnova E, Demidov L,

Keywords: merkel cell carcinoma, merkel cell polyomavirus, immunohistochemistry, prognosis,

#836 Grade Increases In Gastroenteropancreatic Neuroendocrine Tumor Metastases Compared to the Primary Tumor

Introduction: The neuroendocrine tumor (NET) proliferation-based grading system (ENETS/WHO) has proved reliable for prognostic stratification of gastroenteropancreatic tumors (GEP). Although anecdotes have been published, no single study has evaluated whether grade changes between primary site and metastases.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Grillo F

Authors: Grillo F, Brisigotti M, Albertelli M, Borra T, Mastracci L,

Keywords: neuroendocrine, grade, Ki-67,

#523 Metastatic Midgut Carcinoid Tumors: 20-years Experience in a Single Center

Introduction: The prognosis of metastatic midgut carcinoids has improved during the last decade, due to the increasing number of therapeutic options.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Moletta L, Milanetto A, Alaggio R, Sperti C, Pedrazzoli S,

Keywords: midgut carcinoid tumors, metastatic tumors,