Abstract Library

#770 The Axon Guidance Molecules Slit2 and Robo Control Motility and Growth of Pancreatic Neuroendocrine Tumor Cells

Introduction: Dense vascularization and high frequency of metastasis in pancreatic neuroendocrine tumors (pNET) suggest a central role for the interaction of tumor cells and vessels. Slit2 and its receptors Robo1 and Robo4 act as guidance cues in neurogenesis, angiogenesis and epithelial morphogenesis, and hence represent attractive candidate regulators at the tumor cell/stroma interface.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Fischer C

Authors: Detjen K, Hilfenhaus G, Göhrig A, Körner J, Welzel M,

Keywords: Axon guidance, Slit2, Robo, NET, metastases, motility,

#191 Immunohistochemical Analysis of Epithelial-Mesenchymal Transition Markers in Neuroendocrine Tumors of the Lung

Introduction: The increased motility and invasiveness of cancer cells in the first phase of metastasis are reminiscent of epithelial–mesenchymal transition (EMT) during embryonic development.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Galván J, González M, Fonseca P, Folgueras M, Astudillo A,

Keywords: EMT, snail, slug, twist, foxC2, cadherin, pulmonary neuroendocrine tumors ,

#118 Gastrointestinal motility in patients with neuroendocrine tumors

Introduction: Diarrhea is the most common symptom in patients with intestinal neuroendocrine tumors (NET). Somatostatin analogues reduce stool frequency and may increase gastrointestinal transit time (GITT). Motility tracking system® MTS-1 (MTS) (Motilis, Switzerland) is a novel, safe, almost non-invasive and easy-to-perform method for description of gastrointestinal motility.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Gregersen T

Authors: Gregersen T, Gronbaek H, Schlageter V, Fynne L, Worsoe J,

Keywords: neuroendocrine tumor, gastrointestinal motility,