Abstract Library

#4039 Long-term natural history of enterochromaffin-like cell (ECL) hyperplasia

Introduction: Enterochromaffin-like cell (ECL) hyperplasia in the context of autoimmune atrophic gastritis, over a period of time, can progress to gastric neuroendocrine tumors (g-NETs) type 1.

Conference:

Presenting Author:

Authors: Karapanagioti A, Panagaki M, Ioannidou K, Papadopoulou N, Kaltsas G,

Keywords: ECL hyperplasia, g-NET type 1, gastrin,

#3790 Pancreatic neuroendocrine tumors (pNETs) in French VHL mutation carriers – A nationwide retrospective study with genotype-phenotype correlations

Introduction: Von Hippel-Lindau disease (VHL) is a rare inheritable syndrome predisposing to pancreatic neuroendocrine tumors (pNETs). The natural history of VHL-related pNETs is ill-known.

Conference:

Presenting Author:

Authors: Muller M, Hammel P, Sauvanet A, Couvelard A, Vullierme M,

Keywords: hereditary neoplastic syndrome, von Hippel-Lindau disease, VHL gene, pancreatic neuroendocrine tumor,

#3751 Grade 2 gastric carcinoids type 1 – Not always an indolent disease

Introduction: Gastric carcinoids type 1 (GC1) are increasingly recognized and are usually well-differentiated grade 1 neoplasms. However, rare cases of metastatic spread and adverse prognosis have been described in the literature.

Conference:

Presenting Author:

Authors: Tsoli M, Koumarianou A, Karapanagioti A, Daskalakis K, Panagaki M,

Keywords: gastric carcinoid, grade 2,

#3578 Optimal PLAnning of treatment and research of Neuroendocrine Tumors (NETs) in Australia: The PLANET registry and patient reported outcomes via PLANET App

Introduction: Neuroendocrine Neoplasms (NENs) are challenging to diagnose and manage due to their varied behaviour. Despite usually having an indolent course, they are often metastatic at diagnosis and can be associated with significant long-term morbidity and impaired quality-of-life (QOL). The PLANET registry was established to collate clinical data from tertiary NET centres and integrate these with real-time patient reported outcomes (PROs) enabled by the smartphone-based PLANET App.

Conference:

Presenting Author: Leyden S

Authors: Leyden S, Cummins M, Pavlakis N, Ransom D, Price T,

Keywords: data, PROMS, PROs, QOLs, real-world data,

#3374 Gastric metaplasia and duodenal neuroendocrine neoplasms: True causality or simple coincidence?

Introduction: Duodenal neuroendocrine neoplasms (dNENs) are heterogeneous tumors, whose natural history is poorly known. Duodenal gastric metaplasia (DGM) is considered to be a precancerous lesion which is generally related to chronic inflammation as first sign. No data are available regarding its possible role as a risk factors for dNEN occurrence.

Conference:

Presenting Author: Rossi R

Authors: Rossi R, Milanetto A, Andreasi V, Campana D, Coppa J,

Keywords: duodenal neuroendocrine neoplasm, gastric metaplasia,