Abstract Library

#4044 18 F-DOPA PET/CT leading to diagnosis of micro pheochromocytoma

Introduction: Pheochromocytomas are rare neuroendocrine tumors arising from the chromaffin cells of the adrenal medulla. The recent revision in the WHO classification of Endocrine Tumors 2022 has replaced the historical term "nodular hyperplasia" with "micro pheochromocytoma," owing to the presence of similar molecular clonal changes as larger tumors.

Conference:

Presenting Author:

Authors: Roman-Gonzalez A, Arias L, Castellano A, Toro J, Vega I,

Keywords: Pheochromocytoma, PET-CT, Paraganglioma, NGS,

#3828 Role of endoscopic resection margin (R1) in the clinical outcome of patients with neuroendocrine neoplasia

Introduction: Endoscopic resection margin R1 (ER1) describes neoplasia presence at lateral and/or deep margin. Highest rate of R1 resection occurs in duodenal NENs (d-NENs) where advanced resection techniques [endoscopic submucosal dissection (ESD); full thickness resection (EFTR)], are more difficult to apply. In gastric (g-NENs) and rectal NENs (r-NENs), due to favourable anatomy, ESD or EFTR obtain lower rates of R1 resection.

Conference:

Presenting Author: Marasco M

Authors: Marasco M, Massironi S, Campana D, Mosca M, Dell'unto E,

Keywords: neuroendocrine, endoscopy,

#3469 Hedgehog pathway implications in gastroenteropancreatic neuroendocrine tumors

Introduction: Hedgehog (Hh) signaling pathway has a known role in the development of various tumors and we have selective inhibitors. However, its implications in neuroendocrine tumors (NETs) are still to be unrevealed.

Conference:

Presenting Author:

Authors: Saiz-Lopez P, Alcaraz R, Blanco-Abad C, Garcia-Toro E, Garcia-Girón C,

Keywords: Hedgehog, gastroenteropancreatic, prognostic,

#3376 Usefulness of corrected SUV max change in metastatic NET lesions (before and after PRRT) obtained by [68Ga]Ga-DOTA-TATE PET/CT as a prognostic factor

Introduction: Peptide receptor radionuclide therapy (PRRT) is an effective therapeutic option for metastatic neuroendocrine tumor (NET)therapy. The high heterogeneity of the somatostatin receptors (SSTR) density in different NET metastatic lesions and inside single tumors probably influence an clinical outcome. Some studies suggest the response to PRRT assessed on the basis of imaging of SSTR may have a predictive value.

Conference:

Presenting Author:

Authors: Opalinska M, Sowa-Staszczak A, Kania-Kuc A, Al Maraih I, Hubalewska-Dydejczyk A,

Keywords: PRRT, NET, outcome, 68Ga-DOTATATE PET/CT, SSTR expression,

#3328 Role of neoadjuvant PRRT in resectable/borderline resectable PanNETs: Clinical, pathological and genomic features

Introduction: The role of preoperative therapies to obtain cytoreduction, especially PRRT, is unclear.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Fumagalli A

Authors: Fumagalli A, Pellicciari M, Reni A, Borghesani M, Zaninotto E,

Keywords: net, prrt, neuroendocrine tumor, pancreas, genomic, neoadjuvant treatment,