Abstract Library

#3309 Comprehensive genetic analysis of tumor suppressor genes Men1, PTEN, Rb1 and p53 in NETs in mice

Introduction: Tumor suppressor genes (TSGs) RB1, TP53 and PTEN are three of the most commonly mutated TSGs in human cancers. Multiple endocrine neoplasia type 1 (MEN1) gene is one of the most frequently mutated TSGs in human neuroendocrine tumors (NETs). Cooperative effects of genetic alterations of TSGs are frequently observed during carcinogenesis.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Xu E, Vosburgh E, Wong C, Tang L, Levine A,

Keywords: neuroendocrine tumor, men1, rb, pten, p53,

#2093 Genetic Analysis Identifies Subgroups of Small Well-Differentiated Pancreatic Neuroendocrine Tumors with Different Risk for Liver Metastases

Introduction: Small size well-differentiated pancreatic neuroendocrine tumors (PanNETs) behave non-aggressively. However, a limited subset progresses with liver metastases.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Pea A

Authors: Pea A, Yu J, Marchionni L, Noe M, Luchini C,

Keywords: genetic, small tumors, metastases, ALT,

#1579 Establishment and Characterization of a Continuous Cell Line from a Human Familial Medullary Thyroid Carcinoma

Introduction: introduction missing

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Pfragner R, Schwach G, Ghaffari Tabrizi-Wizsy N, Hoeger H, Tam-Amersdorfer C,

Keywords: Familial MTC, continuous cell line, characterisation, authentication, xenografts,

#1329 The MEN2B Due to de Novo Mutation M918T at Algiers

Introduction: The MEN2B, or Gorlin syndrome is a very rare disorder where there are a medullary cancer of thyroide associated with pheochromocytoma and other clinical signs such as a ganglion – neuromatose or a Marfan syndrome. The MEN2B belongs MEN2 are rare hereditary disease, transmitted as an autosomal dominant mutations linked to the RET proto-oncogene.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Chikouche A,

Keywords: MEN2B, de novo mutation, genotypic analysis,

#527 Pheochromocytoma Molecular Analysis After Maternal Transmission of SDHD Mutation Elucidates Mechanism of Parent-of-Origin Effect

Introduction: In SDHD mutation families, paragangliomas and pheochromocytomas usually occur only after paternal transmission of the mutation. This important but unexplained parent-of-origin effect is not due to imprinting of the SDHD gene itself (as was initially suspected) since SDHD is biallelically expressed.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Tobias E, Yeap P, Mavraki E, Fletcher A, Freel M,

Keywords: SDHD, imprinting, paraganglioma,