Abstract Library

#2841 Novelties in Primary and Metastatic GEP-NENs Clinical Outcome Investigation

Introduction: Gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NENs) WHO classification, using strict cut-offs, should reflect their biological features. In real world, strict cut-offs not adequately segregate prognostic groups, in particular on metastasis (M).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Milione M

Authors: Kankava K, Maisonneuve P, Mangogna A, Centonze G, Cattaneo L,

Keywords: Gastro-entero-pancreatic neuroendocrine neoplasms, primary tumor, metastasis, Ki-67, mitoses, tumor deposits, clinical outcomes,

#2166 A Family Bronchial Carcinoid Tumor.

Introduction: Typical and atypical bronchial carcinoids are neuroendocrine tumors of the lung. Family lung carcinoid tumors are rare and have been described as very rarely in literature.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Wassila O

Authors: Ougdi W, Bezzar-Ghomari S,

Keywords: atypical carcinoid, neuroendocrin, tumor, lung, family case.,

#1204 Clinico-Pathologic and Survival Analysis of 211 GastroEnteroPancreatic G3 Neuroendocrine Carcinomas (GEP-NECs)

Introduction: GEP-NECs show Ki67>20% and/or >20 mitoses x10 HPF. Mixed AdenoNeuroendocrine Carcinomas (MANECs) are mixed exocrine-neuroendocrine neoplasms. NECs are associated with poor prognosis but recent findings have suggested that there is a fraction of patients showing a better than expected survival rate.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Milione M

Authors: Milione M, Spada F, Maisonneuve P, Pusceddu S, Spaggiari P,

Keywords: NEC, Ki67, MANEC, PROGNOSIS,

#697 Grading NET: Mitosis and Ki-67 conditio sine qua non?

Introduction: The latest WHO classification for neuroendocrine tumors (NET) defines their grade according to Ki-67 and mitotic index. However, as both parameters are markers for a different part of the cell cycle, their values might not lead to the same grade.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: van Velthuysen M

Authors: Van Velthuysen M, Korse T, Van der Pol A, Tesselaar M, Taal B,

Keywords: grade, Ki-67, mitosis, NET,

#668 Analysis of the Undifferentiated Neuroendocrine Carcinomas (grade 3) from the Czech Neuroendocrine Registry

Introduction: GEP NETs WHO classification 2010 describes well-differentiated tumors grade 1 and grade 2 and neuroendocrine carcinomas grade 3 with high mitotic index over 20 mitoses /10 HPF or Ki 67 over 20%. Pulmonary neuroendocrine tumor classification 2004 describes typical and atypical carcinoid tumor and small-cell and large-cell neuroendocrine carcinomas with mitotic index over 10 mitoses/ 10 HPF.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Sedlackova E, Barkmanova J, Louthan O, Linke Z,

Keywords: neuroendocrine carcinoma, grade 3, neuroendocrine registry ,